Research comparison
MOTS-c vs. SS-31
Two mitochondrial research peptides with opposite approaches: MOTS-c is encoded in the mitochondrial genome and studied via AMPK signalling, while SS-31 (elamipretide) is a synthetic tetrapeptide that binds cardiolipin in the inner mitochondrial membrane.
| Property | MOTS-c | SS-31 (Elamipretid) |
|---|---|---|
| Profile | Mitochondrially encoded 16-amino-acid peptide (MOTS-c) studied in models of glucose and energy metabolism via AMPK signalling. | Elamipretide, a cell-permeable tetrapeptide that accumulates in the inner mitochondrial membrane and binds the phospholipid cardiolipin. |
| Sequence | MRWQEMGYIFYPRKLR | D-Arg-Dmt-Lys-Phe-NH2 |
| Length | 16 amino acids | – |
| Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ | C₃₂H₄₉N₉O₅ |
| Molar mass | 2,174.6 g/mol | 639.8 g/mol |
| CAS | 1627580-64-6 | 736992-21-5 |
| Purity (current batch, HPLC) | 99.05 % | 99.79 % |
| Price per mg from | €0.67 | €3.00 |
In the range
For research and laboratory use only. Not for use in humans or animals. The data summarises literature and lab reports; it is not a recommendation for use.



