What is Bronchogen?
Bronchogen consists of alanine, glutamic acid, aspartic acid and leucine and belongs to the short peptides of the Khavinson research.
More data in the lexicon entry on Bronchogen.
State of research
Bronchogen (Ala-Glu-Asp-Leu) was derived from studies of bronchial tissue. Published work covers differentiation of bronchial epithelial cells in culture, expression of mucosal defence genes and airway inflammation models in rats, for example after exposure to irritants.
The literature on the short bioregulator peptides comes mostly from Vladimir Khavinson's group at the St Petersburg Institute of Bioregulation and Gerontology. The proposed shared mechanism is that di- to tetrapeptides enter the nucleus and interact with DNA and histones, changing how certain genes are read. Independent replications outside this group are rare, and controlled human studies are largely lacking.
Status and quality
Bronchogen is not approved as a medicine. Peptidkauf sells Bronchogen solely as a research reagent for laboratory and in-vitro use and gives no dosing or application advice.
An independent laboratory tests every batch for purity (HPLC), identity and measured content before it goes on sale; the reports and their verification keys are in the lab report archive. The material ships as lyophilised powder in a glass vial; storage and laboratory handling are covered under storage & handling.
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