Peptide lexicon
Prostamax
Synthetic tetrapeptide (Lys-Glu-Asp-Pro) from the group of peptide bioregulators, associated with the prostate.
| Substance class | Peptide |
|---|---|
| Sequence | KEDP |
| Molecular formula | C₂₀H₃₃N₅O₉ |
| Molar mass | 487.5 g/mol |
| Synonyms | Lys-Glu-Asp-Pro |
Structure
Prostamax consists of lysine, glutamic acid, aspartic acid and proline and belongs to the short peptides of the Khavinson research.
State of research
Studies examined chromatin structure in lymphocytes, gene expression in prostate cells and ageing models.
Status
Prostamax is not approved as a medicinal product; studies come mainly from one research group.
Literature
- Effects of short peptides on lymphocyte chromatin in senile subjectsBull Exp Biol Med, 2004 · PMID 15085253 · DOI 10.1023/b:bebm.0000024393.40560.05
- [The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats]Adv Gerontol, 2006 · PMID 17152728
- [The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ]Biofizika, 2004 · PMID 15612551
- Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamaxGeorgian Med News, 2009 · PMID 19359734
- [Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro)]Georgian Med News, 2012 · PMID 23221144
